GPER DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human GPER DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — GPER
Entrez GeneID
2852GeneBank Accession#
NM_001505.2Protein Accession#
NP_001496.1Gene Name
GPER
Gene Alias
CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPR30, LERGU, LERGU2, LyGPR, MGC99678
Gene Description
G protein-coupled estrogen receptor 1
Omim ID
601805Gene Ontology
HyperlinkGene Summary
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq
Other Designations
G protein-coupled receptor 30|IL8-related receptor|OTTHUMP00000115502|chemokine receptor-like 2|constitutively expressed peptide-like receptor|flow-induced endothelial G-protein coupled receptor|heptahelix receptor|leucine rich protein in GPR30 3'UTR
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Interactome
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Disease
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