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GPI rabbit monoclonal antibody

  • Catalog # : H00002821-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human GPI peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human GPI is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human GPI peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2821
  • GeneBank Accession#:
  • GPI
  • Gene Name:
  • GPI
  • Gene Alias:
  • AMF,GNPI,NLK,PGI,PHI,SA-36
  • Gene Description:
  • glucose phosphate isomerase
  • Gene Summary:
  • This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. [provided by RefSeq
  • Other Designations:
  • autocrine motility factor,glucose-6-phosphate isomerase,hexose monophosphate isomerase,hexosephosphate isomerase,neuroleukin,oxoisomerase,phosphoglucose isomerase,phosphohexomutase,phosphohexose isomerase,phosphosaccharomutase,sperm antigen-36
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