GPD2 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (67.69 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant GPD2.
Immunogen
GPD2 (AAH19874, 1 a.a. ~ 378 a.a) full-length recombinant protein with GST tag.
Sequence
MAFQKAVKGTLVGGGALATVLGLSQFAHYRRKQMNLAYVKAADCISEPVNREPPSREAQLLTLQNTSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAIMKLDIEQYRMVKEALHERANLLEIAPHLSAPLPIMLPVYKWWQLPYYWVGIKLYDLVAGSNCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPQTGKVHVSGARCKDVLTGQEFDVRAKCVINATGPFTDSVRKMDDKDAAAICQPSAGVHIVMPGYYSPESMGLLDPATSDGRVIFFLPWQKMTIAGTTDTPTDVTHHPIPSEEDINFILNEV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (92)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (67.69 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — GPD2
Entrez GeneID
2820GeneBank Accession#
BC019874Protein Accession#
AAH19874Gene Name
GPD2
Gene Alias
GDH2, GPDM, mGPDH
Gene Description
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
Gene Ontology
HyperlinkGene Summary
Mitochondrial glycerophosphate dehydrogenase (EC 1.1.99.5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.[supplied by OMIM
Other Designations
mitochondrial glycerophosphate dehydrogenase
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Interactome
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Pathway
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Disease
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Publication Reference
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Examination of bioenergetic function in the inner mitochondrial membrane peptidase 2-like (Immp2l) mutant mice.
Bharadwaj MS, Zhou Y, Molina AJ, Criswell T, Lu B.
Redox Biology 2014 Aug; 2:1008.
Application：WB-Ti, Mouse, Brown adipose.
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A Mutation in the Inner Mitochondrial Membrane Peptidase 2-Like Gene (Immp2l) Affects Mitochondrial Function and Impairs Fertility in Mice.
Lu B, Poirier C, Gaspar T, Gratzke C, Harrison W, Busija D, Matzuk M, Andersson KE, Overbeek PA, Bishop CE.
Biology of Reproduction 2007 Dec; 78(4):601.
Application：WB, Mouse, Mitochondrial protein from brown fat.
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Examination of bioenergetic function in the inner mitochondrial membrane peptidase 2-like (Immp2l) mutant mice.
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