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GP1BA 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00002811-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-GP1BA full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 69
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-GP1BA antibody (H00002811-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00002811-T01
    GP1BA transfected lysate.
    Western Blot
    QC Testing of H00002811-T01
    Lane 1: GP1BA transfected lysate ( 69.00 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2811
  • Gene Name:
  • GP1BA
  • Gene Alias:
  • BSS,CD42B,CD42b-alpha,GP1B,MGC34595
  • Gene Description:
  • glycoprotein Ib (platelet), alpha polypeptide
  • Gene Summary:
  • Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq
  • Other Designations:
  • platelet glycoprotein Ib alpha polypeptide,platelet membrane glycoprotein 1b-alpha subunit
  • Interactome
  • Interactome
  • Related Disease
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