GNB3 monoclonal antibody (M01), clone M1-1-1D5
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More Files
- More Functions
Western Blot (Cell lysate)
GNB3 monoclonal antibody (M01), clone M1-1-1D5 Western Blot analysis of GNB3 expression in HepG2 ( Cat # L019V1 ).
Immunofluorescence
Immunofluorescence of monoclonal antibody to GNB3 on HepG2 cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant GNB3.
Immunogen
GNB3 (AAH02454, 1 a.a. ~ 340 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGEMEQLRQEAEQLKKQIADARKACAGVTLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
GNB3 monoclonal antibody (M01), clone M1-1-1D5 Western Blot analysis of GNB3 expression in HepG2 ( Cat # L019V1 ).ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to GNB3 on HepG2 cell. [antibody concentration 10 ug/ml] -
Gene Info — GNB3
Entrez GeneID
2784GeneBank Accession#
BC002454Protein Accession#
AAH02454Gene Name
GNB3
Gene Alias
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Gene Description
guanine nucleotide binding protein (G protein), beta polypeptide 3
Gene Ontology
HyperlinkGene Summary
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described. [provided by RefSeq
Other Designations
G protein, beta-3 subunit|GTP-binding regulatory protein beta-3 chain|guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3|guanine nucleotide-binding protein, beta-3 subunit|hypertension associated protein|transducin beta chain 3
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Interactome
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Pathway
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Disease
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