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Last updated: 2016/12/4

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GM2A (Human) Recombinant Protein (P01)

  • Catalog # : H00002760-P01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human GM2A full-length ORF ( NP_000396.2, 1 a.a. - 193 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • MQSLMQAPLLIALGLLLAAPAQAHLKKPSQLSSFSWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPLKVDLVLEKEVAGLWIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 47.2
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00002760-P01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 2760
  • Gene Name:
  • GM2A
  • Gene Alias:
  • SAP-3
  • Gene Description:
  • GM2 ganglioside activator
  • Gene Summary:
  • This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. [provided by RefSeq
  • Other Designations:
  • cerebroside sulfate activator protein,sphingolipid activator protein 3
  • Gene Pathway
  • Related Disease
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