GM2A purified MaxPab mouse polyclonal antibody (B02P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of GM2A expression in transfected 293T cell line (H00002760-T02) by GM2A MaxPab polyclonal antibody.
Lane 1: GM2A transfected lysate(21.23 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GM2A protein.
Immunogen
GM2A (NP_000396.2, 1 a.a. ~ 193 a.a) full-length human protein.
Sequence
MQSLMQAPLLIALGLLLAAPAQAHLKKPSQLSSFSWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPLKVDLVLEKEVAGLWIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GM2A expression in transfected 293T cell line (H00002760-T02) by GM2A MaxPab polyclonal antibody.
Lane 1: GM2A transfected lysate(21.23 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GM2A
Entrez GeneID
2760GeneBank Accession#
NM_000405.3Protein Accession#
NP_000396.2Gene Name
GM2A
Gene Alias
SAP-3
Gene Description
GM2 ganglioside activator
Omim ID
272750Gene Ontology
HyperlinkGene Summary
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. [provided by RefSeq
Other Designations
cerebroside sulfate activator protein|sphingolipid activator protein 3
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Interactome
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Pathway
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Disease
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