GLUD1 (Human) Recombinant Protein (P02)
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More Files
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Specification
Product Description
Human GLUD1 full-length ORF (BAG52930.1, 1 a.a. - 515 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MYRYLGPGTARRRPAAGAGIGRPAPLQRGGGRPRGRPQLLQDGGGLLRSRRQHRGGQAGGGPEDPGERGAEAEPGARHPADHQALQPCAESLLPQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTVERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
82.4
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GLUD1
Entrez GeneID
2746GeneBank Accession#
AK094782.1Protein Accession#
BAG52930.1Gene Name
GLUD1
Gene Alias
GDH, GDH1, GLUD, MGC132003
Gene Description
glutamate dehydrogenase 1
Gene Ontology
HyperlinkGene Summary
This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans
Other Designations
OTTHUMP00000020018|glutamate dehydrogenase (NAD(P)+)
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Interactome
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Pathway
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Disease
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