GLRA1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-GLRA1 full-length
Host
Human
Theoretical MW (kDa)
51.7
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GLRA1 antibody (H00002741-D01P) by Western Blots.
SDS-PAGE Gel
GLRA1 transfected lysate.
Western Blot
Lane 1: GLRA1 transfected lysate ( 51.70 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GLRA1
Entrez GeneID
2741GeneBank Accession#
BC074980Protein Accession#
NP_000162.2Gene Name
GLRA1
Gene Alias
MGC138878, MGC138879, STHE
Gene Description
glycine receptor, alpha 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000160616|glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)|startle disease/hyperekplexia|stiff person syndrome
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Interactome
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Disease
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