GLRA1 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human GLRA1 full-length ORF ( NP_000162.2, 1 a.a. - 449 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
78.1
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GLRA1
Entrez GeneID
2741GeneBank Accession#
NM_000171.2Protein Accession#
NP_000162.2Gene Name
GLRA1
Gene Alias
MGC138878, MGC138879, STHE
Gene Description
glycine receptor, alpha 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000160616|glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)|startle disease/hyperekplexia|stiff person syndrome
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Interactomes
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Pathways
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Diseases
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