GLI1 (Human) Recombinant Protein (Q02)
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More Files
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Specification
Product Description
Human GLI1 partial ORF (AAH13000.1, 401 a.a. - 500 a.a.) recombinant protein with GST-pstS1 tag at N-terminal.
Sequence
GPLPRAPSISTVEPKREREGGPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIAGTGLSTLRRLEN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
39.05
Interspecies Antigen Sequence
Mouse (88); Rat (89)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GLI1
Entrez GeneID
2735GeneBank Accession#
BC013000.2Protein Accession#
AAH13000.1Gene Name
GLI1
Gene Alias
GLI
Gene Description
glioma-associated oncogene homolog 1 (zinc finger protein)
Omim ID
165220Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
glioma-associated oncogene homolog (zinc finger protein)|glioma-associated oncogene homolog 1
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Interactome
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Disease
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