GLE1 monoclonal antibody (M03), clone 1D8

Catalog # H00002733-M03

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Size:100 ug
Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Sandwich ELISA (Recombinant protein)
Application

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged GLE1 is 0.1 ng/ml as a capture antibody.

Immunofluorescence
Application

Immunofluorescence

Immunofluorescence of monoclonal antibody to GLE1 on HeLa cell . [antibody concentration 10 ug/ml]

QC Test

Western Blot detection against Immunogen (36.85 KDa) .

  • Specification

    Product Description

    Mouse monoclonal antibody raised against a partial recombinant GLE1.

    Immunogen

    GLE1 (NP_001003722.1, 140 a.a. ~ 240 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    RMKGTEGLRLWQEEQERKVQALSEMASEQLKRFDEWKELKQHKEFQDLREVMEKSSREALGHQEKLKAEHRHRAKILNLKLREAEQQRVKQAEQERLRKEE

    Host

    Mouse

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (91); Rat (92)

    Isotype

    IgG1 Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (36.85 KDa) .

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Recombinant protein)

    Sandwich ELISA (Recombinant protein)

    Detection limit for recombinant GST tagged GLE1 is 0.1 ng/ml as a capture antibody.

    ELISA

    Immunofluorescence

    Immunofluorescence of monoclonal antibody to GLE1 on HeLa cell . [antibody concentration 10 ug/ml]
  • Gene Info — GLE1

    Entrez GeneID

    2733

    GeneBank Accession#

    NM_001003722

    Protein Accession#

    NP_001003722.1

    Gene Name

    GLE1

    Gene Alias

    GLE1L, LCCS, LCCS1, hGLE1

    Gene Description

    GLE1 RNA export mediator homolog (yeast)

    Omim ID

    603371

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    GLE1 RNA export mediator homolog|GLE1 RNA export mediator-like|GLE1-like, RNA export mediator|OTTHUMP00000022280|OTTHUMP00000022281

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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