GLE1L purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
GLE1L MaxPab polyclonal antibody. Western Blot analysis of GLE1L expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of GLE1L expression in transfected 293T cell line by GLE1L MaxPab polyclonal antibody.
Lane 1: GLE1L transfected lysate(76.78 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GLE1L protein.
Immunogen
GLE1L (AAH30012, 1 a.a. ~ 698 a.a) full-length human protein.
Sequence
MPSEGRCWETLKALRSSDKGRLCYYRDWLLRREDVLEECMSLPKLSSYSGWVVEHVLPHMQENQPLSETSPSSTSASALDQPSFVPKSPDASSAFSPASPATPNGTKGKDESQHTESMVLQSSRGIKVEDCVRMYELVHRMKGTEGLRLWQEEQERKVQALSEMASEQLKRFDEWKELKQHKEFQDLREVMEKSSREALGHQEKLKAEHRHRAKILNLKLREAEQQRVKQAEQERLRKEEGQIRLRALYALQEEMLQLSQQLDASEQHKALLKVDLAAFQTRGNQLCSLISGIIRASSESSYPTAESQAEAERALREMRDLLMNLGQEITRACEDKRRQDEEEAQVKLQEAQMQQGPEAHKEPPAPSQGPGGKQNEDLQVKVQDITMQWYQQLQDASMQCVLTFEGLTNSKDSQAKKIKMDLQKAATIPVSQISTIAGSKLKEIFDKIHSLLSGKPVQSGGRSVSVTLNPQGLDFVQYKLAEKFVKQGEEEVASHHEAAFPIAVVASGIWELHPRVGDLILAHLHKKCPYSVPFYPTFKEGMALEDYQRMLGYQVKDSKVEQQDNFLKRMSGMIRLYAAIIQLRWPYGNQQEIHPHGLNHGWRWLAQILNMEPLSDVTATLLFDFLEVCGNALMKQYQVQFWKMLILIKEDYFPRIEAITSSGQMGSFIRLKQFLEKCLQHKDIPVPKGFLTSSFWRS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (83)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GLE1L MaxPab polyclonal antibody. Western Blot analysis of GLE1L expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of GLE1L expression in transfected 293T cell line by GLE1L MaxPab polyclonal antibody.
Lane 1: GLE1L transfected lysate(76.78 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GLE1
Entrez GeneID
2733GeneBank Accession#
BC030012Protein Accession#
AAH30012Gene Name
GLE1
Gene Alias
GLE1L, LCCS, LCCS1, hGLE1
Gene Description
GLE1 RNA export mediator homolog (yeast)
Omim ID
603371Gene Ontology
HyperlinkGene Summary
This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
GLE1 RNA export mediator homolog|GLE1 RNA export mediator-like|GLE1-like, RNA export mediator|OTTHUMP00000022280|OTTHUMP00000022281
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Interactome
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Disease
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