GLDC (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human GLDC partial ORF ( NP_000161.1, 922 a.a. - 1020 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHWDRPYSREVAAFPLPFMKPENKFWPTIARIDDIYGDQHLVCTCPPMEVYESPFSEQKRASS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GLDC
Entrez GeneID
2731GeneBank Accession#
NM_000170Protein Accession#
NP_000161.1Gene Name
GLDC
Gene Alias
GCE, GCSP, HYGN1, MGC138198, MGC138200, NKH
Gene Description
glycine dehydrogenase (decarboxylating)
Gene Ontology
HyperlinkGene Summary
The enzyme system for cleavage of glycine (glycine cleavage system; GCS; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes; see MIM 238310, MIM 238330, and MIM 238331.[supplied by OMIM
Other Designations
OTTHUMP00000044451|glycine cleavage system protein P|glycine decarboxylase P-protein|glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P)
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Interactome
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Pathway
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Disease
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