GLA (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of GLA transfected lysate using rabbit polyclonal anti-GLA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-GLA.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of GLA transfected lysate using rabbit polyclonal anti-GLA and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-GLA.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-GLA (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-GLA (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — GLA
Entrez GeneID
2717Gene Name
GLA
Gene Alias
GALA
Gene Description
galactosidase, alpha
Gene Ontology
HyperlinkGene Summary
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq
Other Designations
OTTHUMP00000023679|agalsidase alfa|alpha-D-galactosidase A|alpha-D-galactoside galactohydrolase 1|alpha-gal A|alpha-galactosidase A|melibiase
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Interactome
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Pathway
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Disease
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