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Last updated: 2017/6/25

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GJB2 rabbit monoclonal antibody

  • Catalog # : H00002706-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human GJB2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human GJB2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human GJB2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2706
  • GeneBank Accession#:
  • GJB2
  • Gene Name:
  • GJB2
  • Gene Alias:
  • CX26,DFNA3,DFNB1,HID,KID,NSRD1,PPK
  • Gene Description:
  • gap junction protein, beta 2, 26kDa
  • Gene Summary:
  • This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018093,OTTHUMP00000018094,connexin 26,gap junction protein beta 2,gap junction protein, beta 2, 26kD (connexin 26)
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