GJB1 monoclonal antibody (M03), clone 2B9
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GJB1.
Immunogen
GJB1 (AAH22426, 75 a.a. ~ 174 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GJB1 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — GJB1
Entrez GeneID
2705GeneBank Accession#
BC022426Protein Accession#
AAH22426Gene Name
GJB1
Gene Alias
CMTX, CMTX1, CX32
Gene Description
gap junction protein, beta 1, 32kDa
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023502|OTTHUMP00000023503|OTTHUMP00000023504|connexin 32
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Interactome
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