GHSR rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human GHSR peptide using ARM Technology.
Immunogen
A synthetic peptide of human GHSR is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human GHSR peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — GHSR
Entrez GeneID
2693GeneBank Accession#
GHSRGene Name
GHSR
Gene Alias
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Gene Description
growth hormone secretagogue receptor
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. [provided by RefSeq
Other Designations
ghrelin receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Erythromycin Inhibits Neutrophilic Inflammation and Mucosal Disease by Upregulating DEL-1.
Tomoki Maekawa, Hikaru Tamura, Hisanori Domon, Takumi Hiyoshi, Toshihito Isono, Daisuke Yonezawa, Naoki Hayashi, Naoki Takahashi, Koichi Tabeta, Takeyasu Maeda, Masataka Oda, Athanasios Ziogas, Vasileia Ι Alexaki, Triantafyllos Chavakis, Yutaka Terao, George Hajishengallis.
JCI Insight 2020 Jun; 5(15):136706.
Application:WB-Tr, Human, Human lung microvascular endothelial cells.
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Erythromycin Inhibits Neutrophilic Inflammation and Mucosal Disease by Upregulating DEL-1.
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