GHRHR (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human GHRHR partial ORF ( NP_000814, 23 a.a. - 132 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
HMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFSTVKII
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (80); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GHRHR
Entrez GeneID
2692GeneBank Accession#
NM_000823Protein Accession#
NP_000814Gene Name
GHRHR
Gene Alias
GHRFR, GHRHRpsv, GRFR
Gene Description
growth hormone releasing hormone receptor
Omim ID
139191Gene Ontology
HyperlinkGene Summary
This gene, expressed in the pituitary, encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. Many alternate transcriptional splice variants encoding different isoforms have been described, but only two have been characterized to date. [provided by RefSeq
Other Designations
GRF receptor|growth hormone-releasing factor receptor|growth hormone-releasing hormone receptor form a|growth hormone-releasing hormone receptor form b|growth hormone-releasing hormone receptor form c
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Interactome
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Pathway
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Disease
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