GHRH (Human) Recombinant Protein (P01)
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Specification
Product Description
Human GHRH full-length ORF ( NP_066567.1, 1 a.a. - 108 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPLWVFFFVILTLSNSSHCSPPPPLTLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARLGRQVDSMWAEQKQMELESILVALLQKHSRNSQG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
38.8
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GHRH
Entrez GeneID
2691GeneBank Accession#
NM_021081.3Protein Accession#
NP_066567.1Gene Name
GHRH
Gene Alias
GHRF, GRF, MGC119781
Gene Description
growth hormone releasing hormone
Omim ID
139190Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. [provided by RefSeq
Other Designations
OTTHUMP00000030915|growth hormone releasing factor|sermorelin|somatocrinin|somatoliberin
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