GGCX (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human GGCX partial ORF ( NP_000812, 533 a.a. - 629 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEYHKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.41
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GGCX
Entrez GeneID
2677GeneBank Accession#
NM_000821Protein Accession#
NP_000812Gene Name
GGCX
Gene Alias
FLJ26629, VKCFD1
Gene Description
gamma-glutamyl carboxylase
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene
Other Designations
vitamin K-dependent gamma-carboxylase
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Interactome
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Disease
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