GFRA1 monoclonal antibody (M03), clone 3E4
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of GFRA1 expression in transfected 293T cell line by GFRA1 monoclonal antibody (M03), clone 3E4.
Lane 1: GFRA1 transfected lysate(50.8 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (35.68 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant GFRA1.
Immunogen
GFRA1 (NP_005255, 32 a.a. ~ 119 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.68 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GFRA1 expression in transfected 293T cell line by GFRA1 monoclonal antibody (M03), clone 3E4.
Lane 1: GFRA1 transfected lysate(50.8 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — GFRA1
Entrez GeneID
2674GeneBank Accession#
NM_005264Protein Accession#
NP_005255Gene Name
GFRA1
Gene Alias
GDNFR, GDNFRA, GFR-ALPHA-1, MGC23045, RET1L, RETL1, TRNR1
Gene Description
GDNF family receptor alpha 1
Omim ID
601496Gene Ontology
HyperlinkGene Summary
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq
Other Designations
GPI-linked anchor protein|Glial cell line-derived neurotrophic factor receptor alpha|OTTHUMP00000020558|OTTHUMP00000020559|PI-linked cell-surface accessory protein|RET ligand 1|TGF-beta related neurotrophic factor receptor 1
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Interactome
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Disease
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