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GDNF 293T Cell Transient Overexpression Lysate(Denatured)   

  • Catalog # : H00002668-T01
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  • 100 uL
  • USD $ 239
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-GDNF full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 23.7
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-GDNF antibody (H00002668-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00002668-T01
    GDNF transfected lysate.
    Western Blot
    QC Testing of H00002668-T01
    Lane 1: GDNF transfected lysate ( 11.11 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2668
  • Gene Name:
  • GDNF
  • Gene Alias:
  • ATF1,ATF2,HFB1-GDNF
  • Gene Description:
  • glial cell derived neurotrophic factor
  • Gene Summary:
  • This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq
  • Other Designations:
  • astrocyte-derived trophic factor,glial cell line derived neurotrophic factor,glial derived neurotrophic factor
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