Products

Western Blot (Transfected lysate)

Immunofluorescence (Transfected cell)

Flow Cytometry (Transfected cell)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

GDI1

Gene Alias

FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGD1A, RABGDIA, XAP-4

Gene Description

GDP dissociation inhibitor 1

Omim ID

Gene Ontology

Gene Summary

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq

Other Designations

OTTHUMP00000032118|mental retardation, X-linked 41|mental retardation, X-linked 48|rab GDP-dissociation inhibitor, alpha