GDI1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human GDI1 full-length ORF ( AAH00317, 1 a.a. - 447 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDEEYDVIVLGTGLTECIPSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLGPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
74.91
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GDI1
Entrez GeneID
2664GeneBank Accession#
BC000317Protein Accession#
AAH00317Gene Name
GDI1
Gene Alias
FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGD1A, RABGDIA, XAP-4
Gene Description
GDP dissociation inhibitor 1
Gene Ontology
HyperlinkGene Summary
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq
Other Designations
OTTHUMP00000032118|mental retardation, X-linked 41|mental retardation, X-linked 48|rab GDP-dissociation inhibitor, alpha
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Interactome
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Publication Reference
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Antibodies in patients with neuropsychiatric systemic lupus erythematosus.
Kimura A, Kanoh Y, Sakurai T, Koumura A, Yamada M, Hayashi Y, Tanaka Y, Hozumi I, Takemura M, Seishima M, Inuzuka T.
Neurology 2010 Apr; 74(17):1372.
Application：WB-Re, Recombinant protein.
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Antibodies in patients with neuropsychiatric systemic lupus erythematosus.
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