GDI1 monoclonal antibody (M12), clone 2C2
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of GDI1 expression in transfected 293T cell line by GDI1 monoclonal antibody (M12), clone 2C2.
Lane 1: GDI1 transfected lysate(50.6 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (74.91 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant GDI1.
Immunogen
GDI1 (AAH12201, 1 a.a. ~ 447 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (74.91 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GDI1 expression in transfected 293T cell line by GDI1 monoclonal antibody (M12), clone 2C2.
Lane 1: GDI1 transfected lysate(50.6 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — GDI1
Entrez GeneID
2664GeneBank Accession#
BC012201Protein Accession#
AAH12201Gene Name
GDI1
Gene Alias
FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGD1A, RABGDIA, XAP-4
Gene Description
GDP dissociation inhibitor 1
Gene Ontology
HyperlinkGene Summary
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq
Other Designations
OTTHUMP00000032118|mental retardation, X-linked 41|mental retardation, X-linked 48|rab GDP-dissociation inhibitor, alpha
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