GDF10 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of GDF10 expression in transfected 293T cell line (H00002662-T01) by GDF10 MaxPab polyclonal antibody.
Lane1:GDF10 transfected lysate(52.58 KDa).
Lane2:Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GDF10 protein.
Immunogen
GDF10 (NP_004953, 1 a.a. ~ 478 a.a) full-length human protein.
Sequence
MAHVPARTSPGPGPQLLLLLLPLFLLLLRDVAGSHRAPAWSALPAAADGLQGDRDLQRHPGDAAATLGPSAQDMVAVHMHRLYEKYSRQGARPGGGNTVRSFRARLEVVDQKAVYFFNLTSMQDSEMILTATFHFYSEPPRWPRALEVLCKPRAKNASGRPLPLGPPTRQHLLFRSLSQNTATQGLLRGAMALAPPPRGLWQAKDISPIVKAARRDGELLLSAQLDSEERDPGVPRPSPYAPYILVYANDLAISEPNSVAVTLQRYDPFPAGDPEPRAAPNNSADPRVRRAAQATGPLQDNELPGLDERPPRAHAQHFHKHQLWPSPFRALKPRPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCACR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GDF10 expression in transfected 293T cell line (H00002662-T01) by GDF10 MaxPab polyclonal antibody.
Lane1:GDF10 transfected lysate(52.58 KDa).
Lane2:Non-transfected lysate.
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Gene Info — GDF10
Entrez GeneID
2662GeneBank Accession#
NM_004962Protein Accession#
NP_004953Gene Name
GDF10
Gene Alias
BMP-3b, BMP3B
Gene Description
growth differentiation factor 10
Omim ID
601361Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000019534|bone morphogenetic protein 3B
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Interactome
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Disease
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Publication Reference
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Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma.
Cheng CW, Hsiao JR, Fan CC, Lo YK, Tzen CY, Wu LW, Fang WY, Cheng AJ, Chen CH, Chang IS, Jiang SS, Chang JY, Lee AY.
Molecular Carcinogenesis 2016 May; 55(5):499.
Application：IHC-P, WB, WB-Tr, Human, Oral squamous cell carcinoma, CGHNK2, CGK6, HOK, HSC-3, OEC-M1, FADU, YD-15, SCC-4, SCC-9, SCC-15, SCC-25, OC3 cells.
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Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma.
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