GDF8 monoclonal antibody (M06), clone 2D8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GDF8.
Immunogen
GDF8 (NP_005250, 241 a.a. ~ 310 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.48 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GDF8 expression in transfected 293T cell line by GDF8 monoclonal antibody (M06), clone 2D8.
Lane 1: GDF8 transfected lysate(42.8 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — MSTN
Entrez GeneID
2660GeneBank Accession#
NM_005259Protein Accession#
NP_005250Gene Name
MSTN
Gene Alias
GDF8
Gene Description
myostatin
Omim ID
601788Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. [provided by RefSeq
Other Designations
growth differentiation factor 8
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Interactome
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Disease
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