GCSH DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GCSH DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MALRVVRSVRALLCTLRAVPLPAAPCPPRPWQLGVGAVRTLRTGPALLSVRKFTEKHEWVTTENGIGTVGISNFAQEALGDVVYCSLPEVGTKLNKQDEFGALESVKAASELYSPLSGEVTEINEALAENPGLVNKSCYEDGWLIKMTLSNPSELDELMSEEAYEKYIKSIEE
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — GCSH
Entrez GeneID
2653GeneBank Accession#
BC000790Protein Accession#
AAH00790.1Gene Name
GCSH
Gene Alias
GCE, NKH
Gene Description
glycine cleavage system protein H (aminomethyl carrier)
Gene Ontology
HyperlinkGene Summary
The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme; MIM 238310), and L protein (a lipoamide dehydrogenase; MIM 238331). Glycine encephalopathy (GCE; MIM 605899), also called nonketotic hyperglycinemia (NKH), may be due to a defect in any one of these enzymes.[supplied by OMIM
Other Designations
lipoic acid-containing protein|mitochondrial glycine cleavage system H-protein|part of mitochondrial matrix glycine cleavage enzyme complex of 4 proteins: H-, L-, P-, and T-proteins
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Interactome
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Disease
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