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GCSH Pre-design Chimera RNAi

  • Catalog # : H00002653-R01
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  • Specification
  • Product Description:
  • Homo sapiens glycine cleavage system protein H (aminomethyl carrier) (GCSH), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004483
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 2653
  • Gene Name:
  • GCSH
  • Gene Alias:
  • GCE,NKH
  • Gene Description:
  • glycine cleavage system protein H (aminomethyl carrier)
  • Gene Summary:
  • The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme; MIM 238310), and L protein (a lipoamide dehydrogenase; MIM 238331). Glycine encephalopathy (GCE; MIM 605899), also called nonketotic hyperglycinemia (NKH), may be due to a defect in any one of these enzymes.[supplied by OMIM
  • Other Designations:
  • lipoic acid-containing protein,mitochondrial glycine cleavage system H-protein,part of mitochondrial matrix glycine cleavage enzyme complex of 4 proteins: H-, L-, P-, and T-proteins
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