GCN5L2 monoclonal antibody (M01), clone 4D3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GCN5L2.
Immunogen
GCN5L2 (AAH32743, 738 a.a. ~ 837 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
GCN5L2 monoclonal antibody (M01), clone 4D3 Western Blot analysis of GCN5L2 expression in K-562 ( Cat # L009V1 ).Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to GCN5L2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — KAT2A
Entrez GeneID
2648GeneBank Accession#
BC032743Protein Accession#
AAH32743Gene Name
KAT2A
Gene Alias
GCN5, GCN5L2, MGC102791, PCAF-b, hGCN5
Gene Description
K(lysine) acetyltransferase 2A
Omim ID
602301Gene Ontology
HyperlinkGene Summary
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM
Other Designations
GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2|GCN5 general control of amino-acid synthesis 5-like 2|General control of amino acid synthesis, yeast, homolog-like 2
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Interactome
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Disease
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