GCHFR 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-GCHFR full-length
Host
Human
Theoretical MW (kDa)
9.7
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GCHFR antibody (H00002644-D01P) by Western Blots.
SDS-PAGE Gel
GCHFR transfected lysate.
Western Blot
Lane 1: GCHFR transfected lysate ( 9.7 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GCHFR
Entrez GeneID
2644GeneBank Accession#
NM_005258Protein Accession#
NP_005249.1Gene Name
GCHFR
Gene Alias
GFRP, HsT16933, MGC138467, MGC138469, P35
Gene Description
GTP cyclohydrolase I feedback regulator
Omim ID
602437Gene Ontology
HyperlinkGene Summary
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq
Other Designations
GTP cyclohydrolase I feedback regulatory protein
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Interactome
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Disease
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