GCHFR (Human) Recombinant Protein (P01)
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Specification
Product Description
Human GCHFR full-length ORF ( NP_005249.1, 1 a.a. - 84 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPYLLISTQIRMEVGPTMVGDEQSDPELMQHLGASKRRALGNNFYEYYVDDPPRIVLDKLERRGFRVLSMTGVGQTLVWCLHKE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.1
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GCHFR
Entrez GeneID
2644GeneBank Accession#
NM_005258.2Protein Accession#
NP_005249.1Gene Name
GCHFR
Gene Alias
GFRP, HsT16933, MGC138467, MGC138469, P35
Gene Description
GTP cyclohydrolase I feedback regulator
Omim ID
602437Gene Ontology
HyperlinkGene Summary
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq
Other Designations
GTP cyclohydrolase I feedback regulatory protein
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Interactome
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Disease
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