GCHFR monoclonal antibody (M01), clone 4G6
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GCHFR is approximately 0.03ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to GCHFR on HeLa cell . [antibody concentration 20 ug/ml]
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GCHFR.
Immunogen
GCHFR (NP_005249.1, 1 a.a. ~ 84 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPYLLISTQIRMEVGPTMVGDEQSDPELMQHLGASKRRALGNNFYEYYVDDPPRIVLDKLERRGFRVLSMTGVGQTLVWCLHKE
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GCHFR is approximately 0.03ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to GCHFR on HeLa cell . [antibody concentration 20 ug/ml] -
Gene Info — GCHFR
Entrez GeneID
2644GeneBank Accession#
NM_005258Protein Accession#
NP_005249.1Gene Name
GCHFR
Gene Alias
GFRP, HsT16933, MGC138467, MGC138469, P35
Gene Description
GTP cyclohydrolase I feedback regulator
Omim ID
602437Gene Ontology
HyperlinkGene Summary
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq
Other Designations
GTP cyclohydrolase I feedback regulatory protein
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Interactome
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Disease
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