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Last updated: 2016/11/27

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GCHFR rabbit monoclonal antibody

  • Catalog # : H00002644-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human GCHFR peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human GCHFR is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human GCHFR peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2644
  • GeneBank Accession#:
  • GCHFR
  • Gene Name:
  • GCHFR
  • Gene Alias:
  • GFRP,HsT16933,MGC138467,MGC138469,P35
  • Gene Description:
  • GTP cyclohydrolase I feedback regulator
  • Gene Summary:
  • GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq
  • Other Designations:
  • GTP cyclohydrolase I feedback regulatory protein
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