Immunoprecipitation of GBE1 transfected lysate using anti-GBE1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with GBE1 purified MaxPab mouse polyclonal antibody (B01P) (H00002632-B01P).
The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease). [provided by RefSeq
amylo-(1,4 to 1,6) transglucosidase,amylo-(1,4 to 1,6) transglycosylase,glycogen branching enzyme,glycogen storage disease type IV