GATM 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-GATM full-length
Host
Human
Theoretical MW (kDa)
46.64
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GATM antibody (H00002628-B01) by Western Blots.
SDS-PAGE Gel
GATM transfected lysate.
Western Blot
Lane 1: GATM transfected lysate ( 46.64 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GATM
Entrez GeneID
2628GeneBank Accession#
NM_001482.1Protein Accession#
NP_001473.1Gene Name
GATM
Gene Alias
AGAT, AT
Gene Description
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Omim ID
602360Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq
Other Designations
L-arginine:glycine amidinotransferase|transamidinase
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Interactome
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Pathway
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Disease
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