GAS2 polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant GAS2.
Immunogen
GAS2 (NP_005247, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag.
Sequence
MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFAR
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — GAS2
Entrez GeneID
2620GeneBank Accession#
NM_005256Protein Accession#
NP_005247Gene Name
GAS2
Gene Alias
MGC32610
Gene Description
growth arrest-specific 2
Omim ID
602835Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.
Kondo Y, Shen L, Cheng AS, Ahmed S, Boumber Y, Charo C, Yamochi T, Urano T, Furukawa K, Kwabi-Addo B, Gold DL, Sekido Y, Huang TH, Issa JP.
Nature Genetics 2008 May; 40(6):741.
Application:WB, Human, MCF-7, PC-3 cells.
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Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.
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