Immunoprecipitation of GART transfected lysate using anti-GART MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with GART purified MaxPab mouse polyclonal antibody (B01P) (H00002618-B01P).
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
OTTHUMP00000068280,OTTHUMP00000068281,OTTHUMP00000068282,OTTHUMP00000068337,trifunctional purine biosynthetic protein adenosine-3