GART purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
GART MaxPab polyclonal antibody. Western Blot analysis of GART expression in human liver.
Western Blot (Cell lysate)
GART MaxPab polyclonal antibody. Western Blot analysis of GART expression in HepG2.
Western Blot (Transfected lysate)
Western Blot analysis of GART expression in transfected 293T cell line (H00002618-T01) by GART MaxPab polyclonal antibody.
Lane 1: GART transfected lysate(47.63 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GART protein.
Immunogen
GART (NP_780294.1, 1 a.a. ~ 433 a.a) full-length human protein.
Sequence
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQFCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFLQQPR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (86)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GART MaxPab polyclonal antibody. Western Blot analysis of GART expression in human liver.Western Blot (Cell lysate)
GART MaxPab polyclonal antibody. Western Blot analysis of GART expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of GART expression in transfected 293T cell line (H00002618-T01) by GART MaxPab polyclonal antibody.
Lane 1: GART transfected lysate(47.63 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GART
Entrez GeneID
2618GeneBank Accession#
NM_175085.1Protein Accession#
NP_780294.1Gene Name
GART
Gene Alias
AIRS, GARS, GARTF, MGC47764, PAIS, PGFT, PRGS
Gene Description
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Omim ID
138440Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000068280|OTTHUMP00000068281|OTTHUMP00000068282|OTTHUMP00000068337|trifunctional purine biosynthetic protein adenosine-3
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Interactome
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Pathway
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Disease
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Publication Reference
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PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
Pelet A, Skopova V, Steuerwald U, Baresova V, Zarhrate M, Plaza JM, Hnizda A, Krijt M, Souckova O, Wibrand F, Andorsdóttir G, Joensen F, Sedlak D, Bleyer AJ, Kmoch S, Lyonnet S, Zikanova M.
Human Molecular Genetics 2019 Nov; 28(22):3805.
Application：IF, Human, Human skin fibroblasts.
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PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
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