GALNS rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human GALNS peptide using ARM Technology.
Immunogen
A synthetic peptide of human GALNS is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human GALNS peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — GALNS
Entrez GeneID
2588GeneBank Accession#
GALNSGene Name
GALNS
Gene Alias
FLJ17434, FLJ42844, FLJ98217, GALNAC6S, GAS, MPS4A
Gene Description
galactosamine (N-acetyl)-6-sulfate sulfatase
Omim ID
253000Gene Ontology
HyperlinkGene Summary
This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq
Other Designations
chondroitinase
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Interactome
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Pathway
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Disease
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