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GALE (Human) IP-WB Antibody Pair

  • Catalog # : H00002582-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00002582-PW1
    Immunoprecipitation of GALE transfected lysate using rabbit polyclonal anti-GALE and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-GALE.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-GALE (300 ul)
    2. Antibody pair for WB: rabbit polyclonal anti-GALE (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2582
  • Gene Name:
  • GALE
  • Gene Alias:
  • FLJ95174,FLJ97302,SDR1E1
  • Gene Description:
  • UDP-galactose-4-epimerase
  • Gene Summary:
  • This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000002991,OTTHUMP00000044857,UDP galactose-4'-epimerase,galactose-4-epimerase, UDP-,galactowaldenase,short chain dehydrogenase/reductase family 1E, member 1
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