GAK MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GAK protein.
Immunogen
GAK (AAH08668.1, 1 a.a. ~ 416 a.a) full-length human protein.
Sequence
MSLLQSALDFLAGPGSLGGASGRDQSDFVGQTVELGELRLLLASPAPPLSVQSTPRGGPPAAADPFGPLLPSSGNNSQPCSNPDLFGEFLNSDSVTVPPSFPSAHSSPPPSCSADFLHLGDLPGEPSKMTASSSNPDLLGGWAAWTETAASAVAPTPATEGPLFSPGGQPAPCGSQASWTKSQNPDPFADLGDLSSGLQGSPAGFPPGGFIPKTATTPKGSSSWQTSRPPAQGASWPPQAKPPPKACTQPRPNYASNFSVIGAREERGVRAPSFAQKPKVSENDFEDLLSNQGFSSRSDKKGPKTIAEMRKQDLAKDTDPLKLKLLDWIEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVAPEQVKKHYRRAVLAVHPDKAAGQPYEQHAKMIFMELNDAWSEFENQGSRPLF
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GAK MaxPab rabbit polyclonal antibody. Western Blot analysis of GAK expression in mouse testis.Western Blot (Transfected lysate)
Western Blot analysis of GAK expression in transfected 293T cell line (H00002580-T02) by GAK MaxPab polyclonal antibody.
Lane 1: GAK transfected lysate(44 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of GAK transfected lysate using anti-GAK MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with GAK purified MaxPab mouse polyclonal antibody (B01P) (H00002580-B01P). -
Gene Info — GAK
Entrez GeneID
2580GeneBank Accession#
BC008668.1Protein Accession#
AAH08668.1Gene Name
GAK
Gene Alias
FLJ16629, FLJ40395, MGC99654
Gene Description
cyclin G associated kinase
Omim ID
602052Gene Ontology
HyperlinkGene Summary
In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. [provided by RefSeq
Other Designations
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Interactome
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Disease
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