GAD2 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of GAD2 transfected lysate using rabbit polyclonal anti-GAD2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-GAD2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-GAD2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-GAD2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — GAD2
Entrez GeneID
2572Gene Name
GAD2
Gene Alias
GAD65, MGC161605, MGC161607
Gene Description
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Omim ID
138275Gene Ontology
HyperlinkGene Summary
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq
Other Designations
Glutamate decarboxylase-2 (pancreas)|OTTHUMP00000019335|OTTHUMP00000019336|glutamate decarboxylase 2|glutamate decarboxylase 2 (pancreatic islets and brain, 65kD)
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Interactome
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Pathway
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Disease
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