GABRD DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human GABRD DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — GABRD
Entrez GeneID
2563GeneBank Accession#
NM_000815.2Protein Accession#
NP_000806.2Gene Name
GABRD
Gene Alias
MGC45284
Gene Description
gamma-aminobutyric acid (GABA) A receptor, delta
Omim ID
137163Gene Ontology
HyperlinkGene Summary
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq
Other Designations
GABA(A) receptor subunit delta|GABA-A receptor, delta polypeptide|OTTHUMP00000038578
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Interactome
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Disease
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