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XRCC6 rabbit monoclonal antibody

  • Catalog # : H00002547-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human XRCC6 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human XRCC6 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human XRCC6 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2547
  • GeneBank Accession#:
  • XRCC6
  • Gene Name:
  • XRCC6
  • Gene Alias:
  • CTC75,CTCBF,G22P1,KU70,ML8,TLAA
  • Gene Description:
  • X-ray repair complementing defective repair in Chinese hamster cells 6
  • Gene Summary:
  • The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq
  • Other Designations:
  • ATP-dependent DNA helicase II, 70 kDa subunit,CTC box binding factor 75 kDa subunit,Ku autoantigen p70 subunit,Ku autoantigen, 70kDa,OTTHUMP00000028581,thyroid autoantigen 70kD (Ku antigen),thyroid autoantigen 70kDa (Ku antigen),thyroid-lupus autoantigen
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