G6PC rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human G6PC peptide using ARM Technology.
Immunogen
A synthetic peptide of human G6PC is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human G6PC peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — G6PC
Entrez GeneID
2538GeneBank Accession#
G6PCGene Name
G6PC
Gene Alias
G6PT, GSD1, GSD1a, MGC163350
Gene Description
glucose-6-phosphatase, catalytic subunit
Omim ID
232200Gene Ontology
HyperlinkGene Summary
Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). [provided by RefSeq
Other Designations
glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease)|glycogen storage disease type I, von Gierke disease
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