FVT1 (Human) Recombinant Protein (P02)
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More Files
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Specification
Product Description
Human FVT1 full-length ORF ( AAH08797.1, 1 a.a. - 332 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
62.15
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KDSR
Entrez GeneID
2531GeneBank Accession#
BC008797Protein Accession#
AAH08797.1Gene Name
KDSR
Gene Alias
DHSR, FLJ36555, FLJ92680, FVT1, SDR35C1
Gene Description
3-ketodihydrosphingosine reductase
Omim ID
136440Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq
Other Designations
3-dehydrosphinganine reductase|KDS reductase|follicular lymphoma variant translocation 1|short chain dehydrogenase/reductase family 35C, member 1
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Interactome
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Pathway
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Disease
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