KDSR rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human KDSR peptide using ARM Technology.
Immunogen
A synthetic peptide of human KDSR is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human KDSR peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — KDSR
Entrez GeneID
2531GeneBank Accession#
KDSRGene Name
KDSR
Gene Alias
DHSR, FLJ36555, FLJ92680, FVT1, SDR35C1
Gene Description
3-ketodihydrosphingosine reductase
Omim ID
136440Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq
Other Designations
3-dehydrosphinganine reductase|KDS reductase|follicular lymphoma variant translocation 1|short chain dehydrogenase/reductase family 35C, member 1
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