FUCA1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human FUCA1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human FUCA1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human FUCA1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — FUCA1
Entrez GeneID
2517GeneBank Accession#
FUCA1Gene Name
FUCA1
Gene Alias
FUCA
Gene Description
fucosidase, alpha-L- 1, tissue
Omim ID
230000Gene Ontology
HyperlinkGene Summary
Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids (Occhiodoro et al., 1989 [PubMed 2803312]). At least 2 separate polymorphic alpha-L-fucosidases are recognized in man: that in tissues, FUCA1, which is deficient in fucosidosis (MIM 230000), and that in plasma, FUCA2 (MIM 136820).[supplied by OMIM
Other Designations
Nbla10230/alpha-L-fucosidase|OTTHUMP00000003009|alpha-L-fucosidase|fucosidase, alpha-L-1, tissue
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